Presentations at the SNO 26th Annual Meeting,

Boston, November 19 – 21, 2021

Oral Presentations

Clinical efficacy of ONC201 in recurrent H3 K27M-mutant diffuse midline glioma patients
Abstract Number: LTBK-05
Date and Time: November 20, 2021 from 9:37 a.m. – 9:50 a.m. ET
Presenter: Isabel Arrillaga-Romany, M.D., Ph. D., Massachusetts General Hospital


Serial plasma and CSF cell-free tumor DNA (cf-tDNA) tracking in diffuse midline glioma patients undergoing treatment with ONC201
Abstract Number: BIOM-28
Date and Time: November 21, 2021 from 11:35 a.m. – 11:45 a.m. ET
Presenter: Evan Cantor, M.D., J.D., Washington University at St. Louis

A Retrospective Observational Study for H3 K27M-mutant Glioma

If you work at a neuro-oncology center that treats patients with midline gliomas, please contact us to learn more about our efforts to better define outcomes in H3 K27M-mutant glioma.

Poster Presentations

Safety of ONC201 administered two consecutive days per week in pediatric H3 K27M-mutant glioma patients
Abstract Number: CTNI-36
Date and Time: November 19, 2021 from 7:30 p.m. – 9:30 p.m. ET
Presenter: Sharon L. Gardner, M.D., New York University School of Medicine


Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose has a strong antiproliferative effect on medulloblastoma cells
Abstract Number: EXTH-68
Date and Time: November 19, 2021 from 7:30 p.m. – 9:30 p.m. ET
Presenter: Georg Karpel-Massler, M.D., Ph.D., Ulm University


Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma
Abstract Number: TAMI-17
Date and Time: November 19, 2021 from 7:30 p.m. – 9:30 p.m. ET
Presenter: Trang T. Nguyen, Ph.D., Colombia University


Harnessing Cellular Stress for Immune Targeting of DIPGs
Abstract Number: EXTH-30
Date and Time: November 19, 2021 from 7:30 p.m. – 9:30 p.m. ET
Presenter: Vidya Gopalakrishnan, Ph.D., University of Texas MD Anderson Cancer Center


Single agent activity of ONC201 in non-midline H3 K27M-mutant diffuse gliomas
Abstract Number: CTNI-27
Date and Time: November 19, 2021 from 7:30 p.m. – 9:30 p.m. ET
Presenter: Yazmin Odia, M.D., M.S., FAAN, Miami Cancer Institute

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